The process of putting a decision or plan into effect; execution.

Testing new medical devices or procedures in terms of safety, effectiveness, and durability should follow the strictest methodological rigor before implementation.

Methodological quality refers to the level of rigor and validity in the design, implementation, and analysis of a research study. In other words, it refers to how well a study has been conducted and how confident we can be in its findings.

Some factors that can affect methodological quality include the sampling method, data collection techniques, the use of appropriate measures and statistical analyses, the control of confounding variables, and the reporting of results. A study with high methodological quality is more likely to produce reliable and accurate results and to be considered trustworthy by other researchers and the scientific community.