cancer

Cancer

Cancer neuroscience is a rapidly growing multidisciplinary field that conceptualizes tumors as tissues fully integrated into the nervous system. Recognizing the complexity and challenges in this field is of fundamental importance to achieving the goal of translational impact for cancer patients 1).


Cancer also known as a malignant tumor or malignant neoplasm, is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

Not all tumors are cancerous; benign tumors do not spread to other parts of the body.

Possible signs and symptoms include a new lump, abnormal bleeding, a prolonged cough, unexplained weight loss, and a change in bowel movements, among others.

While these symptoms may indicate cancer they may also occur due to other issues.

There are over 100 different known cancers that affect humans.


Accumulating evidence revealed that IGF2BP2 mediates the pathogenesis of Type 2 diabetes mellitus and cancer by regulating glucose metabolism, insulin sensitivity, and tumorigenesis. A review provides insight into the potential involvement of this RNA-binding protein in the link between Type 2 diabetes mellitus and cancer 2).


1)
Hwang WL, Perrault EN, Birbrair A, Mattson BJ, Gutmann DH, Mabbott DJ, Cukierman E, Repasky EA, Sloan EK, Zong H, Demir IE, Saloman JL, Borniger JC, Hu J, Dietrich J, Breunig JJ, Çifcibaşı K, Ahmad Kasm KA, Valiente M, Wintermark M, Acharya MM, Scheff NN, D'Silva NJ, Vermeer PD, Wong RJ, Talbot S, Hervey-Jumper SL, Wang TC, Ye Y, Pan Y, Bunimovich YL, Amit M. Integrating priorities at the intersection of cancer and neuroscience. Cancer Cell. 2024 Oct 15:S1535-6108(24)00362-3. doi: 10.1016/j.ccell.2024.09.014. Epub ahead of print. PMID: 39423816.
2)
Cao J, Yan W, Ma X, Huang H, Yan H. Insulin-like growth factor 2 mRNA-binding protein 2 - a potential link between type 2 diabetes mellitus and cancer. J Clin Endocrinol Metab. 2021 Jun 1:dgab391. doi: 10.1210/clinem/dgab391. Epub ahead of print. PMID: 34061963.
  • cancer.txt
  • Last modified: 2024/10/21 08:50
  • by administrador